Can Inhibitors of Snake Venom Phospholipases A(2) Lead to New Insights into Anti-Inflammatory Therapy in Humans? A Theoretical Study

Human phospholipase A(2) (hPLA(2)) of the IIA group (HGIIA) catalyzes the hydrolysis of membrane phospholipids, producing arachidonic acid and originating potent inflammatory mediators. Therefore, molecules that can inhibit this enzyme are a source of potential anti-inflammatory drugs, with differen...

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Detalles Bibliográficos
Autores principales: Sales, Thaís A., Marcussi, Silvana, da Cunha, Elaine F. F., Kuca, Kamil, Ramalho, Teodorico C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705956/
https://www.ncbi.nlm.nih.gov/pubmed/29068410
http://dx.doi.org/10.3390/toxins9110341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705956/
https://www.ncbi.nlm.nih.gov/pubmed/29068410
http://dx.doi.org/10.3390/toxins9110341

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