The Aromatic Head Group of Spider Toxin Polyamines Influences Toxicity to Cancer Cells

Spider venoms constitute incredibly diverse libraries of compounds, many of which are involved in prey capture and defence. Polyamines are often prevalent in the venom and target ionotropic glutamate receptors. Here we show that a novel spider polyamine, PA(366), containing a hydroxyphenyl-based str...

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Detalles Bibliográficos
Autores principales: Wilson, David, Boyle, Glen M., McIntyre, Lachlan, Nolan, Matthew J., Parsons, Peter G., Smith, Jennifer J., Tribolet, Leon, Loukas, Alex, Liddell, Michael J., Rash, Lachlan D., Daly, Norelle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705961/
https://www.ncbi.nlm.nih.gov/pubmed/29077051
http://dx.doi.org/10.3390/toxins9110346

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