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Material-induced Senescence (MIS): Fluidity Induces Senescent Type Cell Death of Lung Cancer Cells via Insulin-Like Growth Factor Binding Protein 5

Objective: We propose here material-induced senescence (MIS) as a new therapeutic concept that limits cancer progression by stable cell cycle arrest. This study examined for the first time the effect of material fluidity on cellular senescence in lung carcinoma using poly(ε-caprolactone-co-D, L-lact...

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Detalles Bibliográficos
Autores principales: Mano, Sharmy Saimon, Uto, Koichiro, Ebara, Mitsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706090/
https://www.ncbi.nlm.nih.gov/pubmed/29187894
http://dx.doi.org/10.7150/thno.20582