Cargando…

miR34a/GOLPH3 Axis abrogates Urothelial Bladder Cancer Chemoresistance via Reduced Cancer Stemness

Rationale: Chemoresistance and subsequent recurrence of human urothelial bladder cancer (UBC) is partially driven by a subpopulation of tumor initiating cells, namely cancer stem cells (CSCs). However, the underlying molecular mechanism in chemotherapy-induced CSCs enrichment and following chemoresi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Qing, Zhuang, Junlong, Deng, Yongming, Yang, Lin, Cao, Wenmin, Chen, Wei, Lin, Tingsheng, Lv, Xiaoyu, Yu, Hang, Xue, Yanshi, Guo, Hongqian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706099/ https://www.ncbi.nlm.nih.gov/pubmed/29187903 http://dx.doi.org/10.7150/thno.21713

Ejemplares similares

GOLPH3 is a potential therapeutic target and a prognostic indicatior of poor survival in bladder cancer treated by cystectomy
por: Zhang, Qing, et al.
Publicado: (2015)

O(2)-generating MnO(2) nanoparticles for enhanced photodynamic therapy of bladder cancer by ameliorating hypoxia
por: Lin, Tingsheng, et al.
Publicado: (2018)

Synergy of Tumor Microenvironment Remodeling and Autophagy Inhibition to Sensitize Radiation for Bladder Cancer Treatment
por: Lin, Tingsheng, et al.
Publicado: (2020)

Allosteric activation of the metabolic enzyme GPD1 inhibits bladder cancer growth via the lysoPC-PAFR-TRPV2 axis
por: Zhang, Wenlong, et al.
Publicado: (2022)

GOLPH3L antagonizes GOLPH3 to determine Golgi morphology
por: Ng, Michelle M., et al.
Publicado: (2013)

Second generation androgen receptor antagonist, TQB3720 abrogates prostate cancer growth via AR/GPX4 axis activated ferroptosis
por: Zhang, Zhongqing, et al.
Publicado: (2023)

GOLPH2 expression in renal cell cancer
por: Fritzsche, Florian Rudolf, et al.
Publicado: (2008)

Oncogenic Roles of GOLPH3 in the Physiopathology of Cancer
por: Sechi, Stefano, et al.
Publicado: (2020)

MiR-1/GOLPH3/Foxo1 Signaling Pathway Regulates Proliferation of Bladder Cancer
por: Liu, Ming-Kai, et al.
Publicado: (2019)

Mass cytometry reveals immune atlas of urothelial carcinoma
por: Zhang, Qing, et al.
Publicado: (2022)

Increased Expression of GOLPH3 is Associated with the Proliferation of Prostate Cancer
por: Li, Wenzhi, et al.
Publicado: (2015)

GOLPH3 and GOLPH3L are broad-spectrum COPI adaptors for sorting into intra-Golgi transport vesicles
por: Welch, Lawrence G., et al.
Publicado: (2021)

GOLPH3 modulates mTOR signaling and rapamycin sensitivity in cancer
por: Scott, Kenneth L., et al.
Publicado: (2009)

The Role of GOLPH3L in the Prognosis and NACT response in Cervical Cancer
por: Feng, Yanling, et al.
Publicado: (2017)

Risk stratification for the prognosis of patients with chemoresistant urothelial cancer treated with pembrolizumab
por: Kobayashi, Takashi, et al.
Publicado: (2020)

TGFβ1 Promotes Gemcitabine Resistance through Regulating the LncRNA-LET/NF90/miR-145 Signaling Axis in Bladder Cancer
por: Zhuang, Junlong, et al.
Publicado: (2017)

Quercetin abrogates chemoresistance in melanoma cells by modulating ΔNp73
por: Thangasamy, Thilakavathy, et al.
Publicado: (2010)

circDHTKD1 promotes lymphatic metastasis of bladder cancer by upregulating CXCL5
por: Lu, Qun, et al.
Publicado: (2022)

GOLPH3 keeps the Golgi residents at home
por: Lowe, Martin
Publicado: (2021)

Xenopus as a Model System for the Study of GOLPH2/GP73 Function: Xenopus golph2 Is Required for Pronephros Development
por: Li, Leike, et al.
Publicado: (2012)

Mechanisms of GOLPH3 Associated with the Progression of Gastric Cancer: A Preliminary Study
por: Peng, Jinzhen, et al.
Publicado: (2014)

GOLPH3L is a Novel Prognostic Biomarker for Epithelial Ovarian Cancer
por: Feng, Yanling, et al.
Publicado: (2015)

FAP-a and GOLPH3 Are Hallmarks of DCIS Progression to Invasive Breast Cancer
por: Yu, Li-Na, et al.
Publicado: (2019)

Urothelial Bladder Cancer Urinary Biomarkers
por: Noon, Aidan P, et al.
Publicado: (2014)

CAD/POLD2 gene expression is associated with poor overall survival and chemoresistance in bladder urothelial carcinoma
por: Givechian, Kevin B., et al.
Publicado: (2018)

Effect of GOLPH3 on cumulus granulosa cell apoptosis and ICSI pregnancy outcomes
por: Lin, Dianliang, et al.
Publicado: (2017)

Tenacissoside H Induces Apoptosis and Inhibits Migration of Colon Cancer Cells by Downregulating Expression of GOLPH3 Gene
por: Hong, Zhong-Shi, et al.
Publicado: (2020)

Metformin and ICG-001 Act Synergistically to Abrogate Cancer Stem Cells-Mediated Chemoresistance in Colorectal Cancer by Promoting Apoptosis and Autophagy
por: Roy, Souvick, et al.
Publicado: (2022)

TGFβ1 secreted by cancer-associated fibroblasts induces epithelial-mesenchymal transition of bladder cancer cells through lncRNA-ZEB2NAT
por: Zhuang, Junlong, et al.
Publicado: (2015)

Protosappanin B Exerts Anti-tumor Effects on Colon Cancer Cells via Inhibiting GOLPH3 Expression
por: Zheng, Xue-Cong, et al.
Publicado: (2020)

Expression of GOLPH3 protein in colon cancer tissues and its association with the prognosis of patients
por: Zhou, Bo, et al.
Publicado: (2016)

Expression of GOLPH3 in patients with non-small cell lung cancer and xenografts models
por: Tang, Shicong, et al.
Publicado: (2018)

GOLPH3 and YB-1 Are Novel Markers Correlating With Poor Prognosis in Prostate Cancer
por: El-Maqsoud, Nehad M. R. Abd, et al.
Publicado: (2015)

Correlation of GOLPH3 Gene with Wnt Signaling Pathway in Human Colon Cancer Cells
por: Qiu, Cheng-Zhi, et al.
Publicado: (2016)

Tropomyosins: Potential Biomarkers for Urothelial Bladder Cancer
por: Humayun-Zakaria, Nada, et al.
Publicado: (2019)

Cost of illness of urothelial bladder cancer in Italy
por: Gerace, Claudio, et al.
Publicado: (2017)

Penile metastasis secondary to urothelial bladder cancer
por: Dolny, Maciej, et al.
Publicado: (2023)

Combination chemotherapy with Zyflamend reduced the acquired resistance of bladder cancer cells to cisplatin through inhibiting NFκB signaling pathway
por: Xue, Yanshi, et al.
Publicado: (2018)

GOLPH3 overexpression correlates with tumor progression and poor prognosis in patients with clinically N0 oral tongue cancer
por: Li, Huan, et al.
Publicado: (2012)

Immunotherapy in the Treatment of Urothelial Bladder Cancer: Insights From Single-Cell Analysis
por: Zang, Jingyu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_unuos4iljh66kkc2sbjd9gp7ub