RAC3 influences the chemoresistance of colon cancer cells through autophagy and apoptosis inhibition

BACKGROUND: RAC3 coactivator overexpression has been implicated in tumorigenesis, contributing to inhibition of apoptosis and autophagy. Both mechanisms are involved in resistance to treatment with chemotherapeutic agents. The aim of this study was to investigate its role in chemoresistance of color...

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Detalles Bibliográficos
Autores principales: Rubio, María Fernanda, Lira, María Cecilia, Rosa, Francisco Damián, Sambresqui, Adrían Dario, Salazar Güemes, María Cecilia, Costas, Mónica Alejandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706160/
https://www.ncbi.nlm.nih.gov/pubmed/29209153
http://dx.doi.org/10.1186/s12935-017-0483-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706160/
https://www.ncbi.nlm.nih.gov/pubmed/29209153
http://dx.doi.org/10.1186/s12935-017-0483-x

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