Arginase 1 deletion in myeloid cells affects the inflammatory response in allergic asthma, but not lung mechanics, in female mice

BACKGROUND: (Over-)expression of arginase may limit local availability of arginine for nitric oxide synthesis. We investigated the significance of arginase1 (ARG1) for the development of airway hyperresponsiveness (AHR) and lung inflammation in female mice with ovalbumin (OVA)-induced allergic asthm...

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Detalles Bibliográficos
Autores principales: Cloots, Roy H. E., Sankaranarayanan, Selvakumari, Poynter, Matthew E., Terwindt, Els, van Dijk, Paul, Lamers, Wouter H., Eleonore Köhler, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706166/
https://www.ncbi.nlm.nih.gov/pubmed/29183288
http://dx.doi.org/10.1186/s12890-017-0490-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706166/
https://www.ncbi.nlm.nih.gov/pubmed/29183288
http://dx.doi.org/10.1186/s12890-017-0490-7

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