Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients

BACKGROUND: Controversies exist as to whether the genetic polymorphisms of the enzymes responsible for the metabolism of tamoxifen can predict breast cancer outcome in patients using adjuvant tamoxifen. Direct measurement of concentrations of active tamoxifen metabolites in serum may be a more biolo...

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Detalles Bibliográficos
Autores principales: Helland, Thomas, Henne, Nina, Bifulco, Ersilia, Naume, Bjørn, Borgen, Elin, Kristensen, Vessela N., Kvaløy, Jan T., Lash, Timothy L., Alnæs, Grethe I. G., van Schaik, Ron H., Janssen, Emiel A. M., Hustad, Steinar, Lien, Ernst A., Mellgren, Gunnar, Søiland, Håvard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706168/
https://www.ncbi.nlm.nih.gov/pubmed/29183390
http://dx.doi.org/10.1186/s13058-017-0916-4

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