Smad4 SUMOylation is essential for memory formation through upregulation of the skeletal myopathy gene TPM2

BACKGROUND: Smad4 is a critical effector of TGF-β signaling that regulates a variety of cellular functions. However, its role in the brain has rarely been studied. Here, we examined the molecular mechanisms underlying the post-translational regulation of Smad4 function by SUMOylation, and its role i...

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Detalles Bibliográficos
Autores principales: Hsu, Wei L., Ma, Yun L., Liu, Yen C., Lee, Eminy H. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706330/
https://www.ncbi.nlm.nih.gov/pubmed/29183317
http://dx.doi.org/10.1186/s12915-017-0452-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706330/
https://www.ncbi.nlm.nih.gov/pubmed/29183317
http://dx.doi.org/10.1186/s12915-017-0452-9

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