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Fungal 7-epi-10-deacetyltaxol produced by an endophytic Pestalotiopsis microspora induces apoptosis in human hepatocellular carcinoma cell line (HepG2)

BACKGROUND: Paclitaxel (taxol) is a potent anticancer drug that is used in the treatment of a wide variety of cancerous. In the present study, we identified a taxol derivative named 7-epi-10-deacetyltaxol (EDT) from the culture of an endophytic fungus Pestalotiopsis microspora isolated from the bark...

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Detalles Bibliográficos
Autores principales:	Subban, Kamalraj, Singh, Satpal, Subramani, Ramesh, Johnpaul, Muthumary, Chelliah, Jayabaskaran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706334/ https://www.ncbi.nlm.nih.gov/pubmed/29183320 http://dx.doi.org/10.1186/s12906-017-1993-8

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