Cargando…

Selective Angiographic Embolization of Blunt Hepatic Trauma Reduces Failure Rate of Nonoperative Therapy and Incidence of Post-Traumatic Complications

BACKGROUND: Conflict still remains as to the benefit of angioembolization (AE) for non-operative therapy (NOT) of blunt hepatic trauma (BHT). The aim of this study was to determine whether AE could result in lower failure rates in hemodynamically stable BHT patients with high failure risk factors fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Han, Jie, Li, Kejian, Sun, Xiaojun, He, Chengli, Liu, Hongyi, Zhang, Yalin, Kong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706383/
https://www.ncbi.nlm.nih.gov/pubmed/29155699
http://dx.doi.org/10.12659/MSM.905115
_version_ 1783282218254204928
author Xu, Han
Jie, Li
Kejian, Sun
Xiaojun, He
Chengli, Liu
Hongyi, Zhang
Yalin, Kong
author_facet Xu, Han
Jie, Li
Kejian, Sun
Xiaojun, He
Chengli, Liu
Hongyi, Zhang
Yalin, Kong
author_sort Xu, Han
collection PubMed
description BACKGROUND: Conflict still remains as to the benefit of angioembolization (AE) for non-operative therapy (NOT) of blunt hepatic trauma (BHT). The aim of this study was to determine whether AE could result in lower failure rates in hemodynamically stable BHT patients with high failure risk factors for NOT, and to systematically evaluate the effectiveness of AE for NOT of BHT. MATERIAL/METHODS: Medical records of all BHT patients from January 1, 1998 to December 31, 2015 at a large trauma center were collected and analyzed. Failure of NOT (FNOT) occurred if hepatic surgery was performed after attempted NOT. Logistic regression analysis was used to identify factors associated with FNOT. Hepatobiliary complications related to hepatic trauma during follow-up were reviewed. RESULTS: No significant difference in FNOT for the no angiographic embolization (NO-AE) group versus angiographic embolization (AE) group was found in hepatic trauma of grades I, II, and V. However, decrease in FNOT was significant with AE performed for hepatic trauma of grades III to IV. Risk factors for FNOT included grade III to IV injuries and contrast blush on CT. Follow-up data of six months also showed that the incidence of hepatobiliary complications in the NO-AE group was higher than the AE group. CONCLUSIONS: Hemodynamically stable BHT patients with grade III to IV injuries, contrast blush on initial CT, and/or decreasing hemoglobin levels can be candidates for selective AE during NOT course.
format Online
Article
Text
id pubmed-5706383
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher International Scientific Literature, Inc.
record_format MEDLINE/PubMed
spelling pubmed-57063832017-11-30 Selective Angiographic Embolization of Blunt Hepatic Trauma Reduces Failure Rate of Nonoperative Therapy and Incidence of Post-Traumatic Complications Xu, Han Jie, Li Kejian, Sun Xiaojun, He Chengli, Liu Hongyi, Zhang Yalin, Kong Med Sci Monit Clinical Research BACKGROUND: Conflict still remains as to the benefit of angioembolization (AE) for non-operative therapy (NOT) of blunt hepatic trauma (BHT). The aim of this study was to determine whether AE could result in lower failure rates in hemodynamically stable BHT patients with high failure risk factors for NOT, and to systematically evaluate the effectiveness of AE for NOT of BHT. MATERIAL/METHODS: Medical records of all BHT patients from January 1, 1998 to December 31, 2015 at a large trauma center were collected and analyzed. Failure of NOT (FNOT) occurred if hepatic surgery was performed after attempted NOT. Logistic regression analysis was used to identify factors associated with FNOT. Hepatobiliary complications related to hepatic trauma during follow-up were reviewed. RESULTS: No significant difference in FNOT for the no angiographic embolization (NO-AE) group versus angiographic embolization (AE) group was found in hepatic trauma of grades I, II, and V. However, decrease in FNOT was significant with AE performed for hepatic trauma of grades III to IV. Risk factors for FNOT included grade III to IV injuries and contrast blush on CT. Follow-up data of six months also showed that the incidence of hepatobiliary complications in the NO-AE group was higher than the AE group. CONCLUSIONS: Hemodynamically stable BHT patients with grade III to IV injuries, contrast blush on initial CT, and/or decreasing hemoglobin levels can be candidates for selective AE during NOT course. International Scientific Literature, Inc. 2017-11-20 /pmc/articles/PMC5706383/ /pubmed/29155699 http://dx.doi.org/10.12659/MSM.905115 Text en © Med Sci Monit, 2017 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Clinical Research
Xu, Han
Jie, Li
Kejian, Sun
Xiaojun, He
Chengli, Liu
Hongyi, Zhang
Yalin, Kong
Selective Angiographic Embolization of Blunt Hepatic Trauma Reduces Failure Rate of Nonoperative Therapy and Incidence of Post-Traumatic Complications
title Selective Angiographic Embolization of Blunt Hepatic Trauma Reduces Failure Rate of Nonoperative Therapy and Incidence of Post-Traumatic Complications
title_full Selective Angiographic Embolization of Blunt Hepatic Trauma Reduces Failure Rate of Nonoperative Therapy and Incidence of Post-Traumatic Complications
title_fullStr Selective Angiographic Embolization of Blunt Hepatic Trauma Reduces Failure Rate of Nonoperative Therapy and Incidence of Post-Traumatic Complications
title_full_unstemmed Selective Angiographic Embolization of Blunt Hepatic Trauma Reduces Failure Rate of Nonoperative Therapy and Incidence of Post-Traumatic Complications
title_short Selective Angiographic Embolization of Blunt Hepatic Trauma Reduces Failure Rate of Nonoperative Therapy and Incidence of Post-Traumatic Complications
title_sort selective angiographic embolization of blunt hepatic trauma reduces failure rate of nonoperative therapy and incidence of post-traumatic complications
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706383/
https://www.ncbi.nlm.nih.gov/pubmed/29155699
http://dx.doi.org/10.12659/MSM.905115
work_keys_str_mv AT xuhan selectiveangiographicembolizationofblunthepatictraumareducesfailurerateofnonoperativetherapyandincidenceofposttraumaticcomplications
AT jieli selectiveangiographicembolizationofblunthepatictraumareducesfailurerateofnonoperativetherapyandincidenceofposttraumaticcomplications
AT kejiansun selectiveangiographicembolizationofblunthepatictraumareducesfailurerateofnonoperativetherapyandincidenceofposttraumaticcomplications
AT xiaojunhe selectiveangiographicembolizationofblunthepatictraumareducesfailurerateofnonoperativetherapyandincidenceofposttraumaticcomplications
AT chengliliu selectiveangiographicembolizationofblunthepatictraumareducesfailurerateofnonoperativetherapyandincidenceofposttraumaticcomplications
AT hongyizhang selectiveangiographicembolizationofblunthepatictraumareducesfailurerateofnonoperativetherapyandincidenceofposttraumaticcomplications
AT yalinkong selectiveangiographicembolizationofblunthepatictraumareducesfailurerateofnonoperativetherapyandincidenceofposttraumaticcomplications