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Host-guest interaction of β-cyclodextrin with isomeric ursolic acid and oleanolic acid: physicochemical characterization and molecular modeling study
Ursolic acid (UA) and oleanolic acid (OA) are insoluble drugs. The objective of this study was to encapsulate them into β-cyclodextrin (β-CD) and compare the solubility and intermolecular force of β-CD with the two isomeric triterpenic acids. The host-guest interaction was explored in liquid and sol...
Autores principales: | Huang, Yuan, Quan, Peng, Wang, Yongwei, Zhang, Dongsheng, Zhang, Mingwan, Li, Rui, Jiang, Nan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial Department of Journal of Biomedical Research
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706432/ https://www.ncbi.nlm.nih.gov/pubmed/28958995 http://dx.doi.org/10.7555/JBR.31.20160073 |
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