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Metformin ameliorates BSCB disruption by inhibiting neutrophil infiltration and MMP‐9 expression but not direct TJ proteins expression regulation
Blood‐spinal cord barrier (BSCB) disruption is a major process for the secondary injury of spinal cord injury (SCI) and is considered to be a therapeutic target for SCI. Previously, we demonstrated that metformin could improve functional recovery after SCI; however, the effect of metformin on BSCB i...
Autores principales: | Zhang, Di, Tang, Qian, Zheng, Gang, Wang, Chenggui, Zhou, Yifei, Wu, Yaosen, Xuan, Jun, Tian, Naifeng, Wang, Xiangyang, Wu, Yan, Xu, Huazi, Zhang, Xiaolei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706495/ https://www.ncbi.nlm.nih.gov/pubmed/28699677 http://dx.doi.org/10.1111/jcmm.13235 |
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