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Folate deficiency disturbs hsa‐let‐7 g level through methylation regulation in neural tube defects

Folic acid deficiency during pregnancy is believed to be a high‐risk factor for neural tube defects (NTDs). Disturbed epigenetic modifications, including miRNA regulation, have been linked to the pathogenesis of NTDs in those with folate deficiency. However, the mechanism by which folic acid‐regulat...

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Detalles Bibliográficos
Autores principales: Wang, Li, Shangguan, Shaofang, Xin, Yu, Chang, Shaoyan, Wang, Zhen, Lu, Xiaolin, Wu, Lihua, Niu, Bo, Zhang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706510/
https://www.ncbi.nlm.nih.gov/pubmed/28631291
http://dx.doi.org/10.1111/jcmm.13228

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