CD19 regulates ADAM28‐mediated Notch2 cleavage to control the differentiation of marginal zone precursors to MZ B cells

As the first line of defence, marginal zone (MZ) B cells play principal roles in clearing blood‐borne pathogens during infection and are over‐primed in autoimmune diseases. However, the basic mechanisms underlying MZ B‐cell development are still unclear. We found here that CD19 deficiency blocked th...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Zhu, Gaizhi, Xiao, He, Liu, Xiaoling, Han, Gencheng, Chen, Guojiang, Hou, Chunmei, Shen, Beifen, Li, Yan, Ma, Ning, Wang, Renxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706524/
https://www.ncbi.nlm.nih.gov/pubmed/28707394
http://dx.doi.org/10.1111/jcmm.13276

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