A positive feedback loop promotes HIF‐1α stability through miR‐210‐mediated suppression of RUNX3 in paraquat‐induced EMT

Irreversible pulmonary fibrosis induced by paraquat (PQ) poisoning is the major cause of death in patients with PQ poisoning. The epithelial–mesenchymal transition (EMT) is postulated to be one of the main mechanisms of pulmonary fibrosis. Here, we investigated the role of miR‐210 in PQ‐induced EMT...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Yong, Wang, Jinfeng, Meng, Xiaoxiao, Xie, Hui, Tan, Jiuting, Guo, Xinkun, Han, Peng, Wang, Ruilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706527/
https://www.ncbi.nlm.nih.gov/pubmed/28699703
http://dx.doi.org/10.1111/jcmm.13264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706527/
https://www.ncbi.nlm.nih.gov/pubmed/28699703
http://dx.doi.org/10.1111/jcmm.13264

Ejemplares similares