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Rictor regulates the vasculogenic mimicry of melanoma via the AKT‐MMP‐2/9 pathway
Vasculogenic mimicry (VM)‐positive melanomas are usually associated with poor prognosis. Rictor, the key component of the rapamycin‐insensitive complex of mTOR (mTORC2), is up‐regulated in several cancers, especially in melanomas with poor prognosis. The aim of this study was to investigate the role...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706568/ https://www.ncbi.nlm.nih.gov/pubmed/28699701 http://dx.doi.org/10.1111/jcmm.13268 |