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Rictor regulates the vasculogenic mimicry of melanoma via the AKT‐MMP‐2/9 pathway

Vasculogenic mimicry (VM)‐positive melanomas are usually associated with poor prognosis. Rictor, the key component of the rapamycin‐insensitive complex of mTOR (mTORC2), is up‐regulated in several cancers, especially in melanomas with poor prognosis. The aim of this study was to investigate the role...

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Detalles Bibliográficos
Autores principales: Liang, Xingmei, Sun, Ran, Zhao, Xiulan, Zhang, Yanhui, Gu, Qiang, Dong, Xueyi, Zhang, Danfang, Sun, Junying, Sun, Baocun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706568/
https://www.ncbi.nlm.nih.gov/pubmed/28699701
http://dx.doi.org/10.1111/jcmm.13268

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