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Activation of GSK‐3 disrupts cholinergic homoeostasis in nucleus basalis of Meynert and frontal cortex of rats

The cholinergic impairment is an early marker in Alzheimer's disease (AD), while the mechanisms are not fully understood. We investigated here the effects of glycogen synthase kinse‐3 (GSK‐3) activation on the cholinergic homoeostasis in nucleus basalis of Meynert (NBM) and frontal cortex, the...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Tian, Qing, Liu, En‐Jie, Zhao, Li, Song, Jie, Liu, Xin‐An, Ren, Qing‐Guo, Jiang, Xia, Zeng, Juan, Yang, Yu‐Tao, Wang, Jian‐Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706587/
https://www.ncbi.nlm.nih.gov/pubmed/28656644
http://dx.doi.org/10.1111/jcmm.13262