Lipid-lowering interventions targeting proprotein convertase subtilisin/kexin type 9 (PCSK9): an emerging chapter in lipid-lowering therapy

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease that is mainly expressed in the liver but can also be found in the intestine and kidneys. PCSK9 promotes the degradation of low density lipoprotein receptors (LDLR) by reducing their recycling and targeting the receptors for...

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Detalles Bibliográficos
Autores principales: Kosmas, Constantine E, DeJesus, Eddy, Morcelo, Rosmery, Garcia, Frank, Montan, Peter D, Guzman, Eliscer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioExcel Publishing Ltd 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706592/
https://www.ncbi.nlm.nih.gov/pubmed/29209403
http://dx.doi.org/10.7573/dic.212511

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