Parallel arrangements of positive feedback loops limit cell-to-cell variability in differentiation

Cellular differentiations are often regulated by bistable switches resulting from specific arrangements of multiple positive feedback loops (PFL) fused to one another. Although bistability generates digital responses at the cellular level, stochasticity in chemical reactions causes population hetero...

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Detalles Bibliográficos
Autores principales: Dey, Anupam, Barik, Debashis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706692/
https://www.ncbi.nlm.nih.gov/pubmed/29186174
http://dx.doi.org/10.1371/journal.pone.0188623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706692/
https://www.ncbi.nlm.nih.gov/pubmed/29186174
http://dx.doi.org/10.1371/journal.pone.0188623

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