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Analysis of DNA topology of EBV minichromosomes in HEK 293 cells

Simian Virus 40 (SV40) and Epstein-Barr Virus (EBV) are frequently used as model systems to study DNA replication. Their genomes are both circular duplex DNAs organized in a single replicon where replication initiates at a precise site upon binding of a specific protein: the large tumor (T) antigen...

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Detalles Bibliográficos
Autores principales: Castán, Alicia, Fernández-Calleja, Vanessa, Hernández, Pablo, Krimer, Dora B., Schvartzman, Jorge B., Fernández-Nestosa, María-José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706722/
https://www.ncbi.nlm.nih.gov/pubmed/29186176
http://dx.doi.org/10.1371/journal.pone.0188172