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Mocetinostat combined with gemcitabine for the treatment of leiomyosarcoma: Preclinical correlates

Leiomyosarcoma (LMS) is a malignant soft tissue sarcoma (STS) with a dismal prognosis following metastatic disease. Chemotherapeutic intervention has demonstrated to have modest clinical efficacy with no curative potential in LMS patients. Previously, we demonstrated pan-HDAC inhibition to have a su...

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Detalles Bibliográficos
Autores principales: Lopez, Gonzalo, Braggio, Danielle, Zewdu, Abeba, Casadei, Lucia, Batte, Kara, Bid, Hemant Kumar, Koller, David, Yu, Peter, Iwenofu, Obiajulu Hans, Strohecker, Anne, Choy, Edwin, Lev, Dina, Pollock, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706733/
https://www.ncbi.nlm.nih.gov/pubmed/29186204
http://dx.doi.org/10.1371/journal.pone.0188859