Cargando…

PKA activation and endothelial claudin-5 breakdown in the schizophrenic prefrontal cortex

Schizophrenia is thought to be caused by a combination of genetic and environmental factors; however, its pathogenesis remains largely unknown. Here, we focus on the endothelial tight-junction protein claudin-5 (CLDN5), because the CLDN5 gene is mapped to the schizophrenia-associated 22q11.2 deletio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nishiura, Keisuke, Ichikawa-Tomikawa, Naoki, Sugimoto, Kotaro, Kunii, Yasuto, Kashiwagi, Korehito, Tanaka, Mizuko, Yokoyama, Yuichi, Hino, Mizuki, Sugino, Takashi, Yabe, Hirooki, Takahashi, Hitoshi, Kakita, Akiyoshi, Imura, Tetsuya, Chiba, Hideki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper: Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706803/ https://www.ncbi.nlm.nih.gov/pubmed/29212157 http://dx.doi.org/10.18632/oncotarget.21850

Ejemplares similares

Serotonin/5-HT1A Signaling in the Neurovascular Unit Regulates Endothelial CLDN5 Expression
por: Sugimoto, Kotaro, et al.
Publicado: (2020)

Liver X receptor reduces proliferation of human oral cancer cells by promoting cholesterol efflux via up-regulation of ABCA1 expression
por: Kaneko, Tetsuharu, et al.
Publicado: (2015)

Differential protein expression of DARPP-32 versus Calcineurin in the prefrontal cortex and nucleus accumbens in schizophrenia and bipolar disorder
por: Kunii, Yasuto, et al.
Publicado: (2019)

Evidence for increased DNA damage repair in the postmortem brain of the high stress-response group of schizophrenia
por: Shishido, Risa, et al.
Publicado: (2023)

Identification of schizophrenia symptom-related gene modules by postmortem brain transcriptome analysis
por: Miyahara, Kazusa, et al.
Publicado: (2023)

Detailed Postmortem Profiling of Inflammatory Mediators Expression Revealed Post-inflammatory Alternation in the Superior Temporal Gyrus of Schizophrenia
por: Izumi, Ryuta, et al.
Publicado: (2021)

Evidence for Altered Phosphoinositide Signaling-Associated Molecules in the Postmortem Prefrontal Cortex of Patients with Schizophrenia
por: Kunii, Yasuto, et al.
Publicado: (2021)

The Src-Family Kinases SRC and BLK Contribute to the CLDN6-Adhesion Signaling
por: Ichikawa-Tomikawa, Naoki, et al.
Publicado: (2023)

Decreased calcineurin immunoreactivity in the postmortem brain of a patient with schizophrenia who had been prescribed the calcineurin inhibitor, tacrolimus, for leukemia
por: Wada, Akira, et al.
Publicado: (2016)

Tubulin/microtubules as novel clozapine targets
por: Hino, Mizuki, et al.
Publicado: (2021)

A case of paroxysmal kinesigenic dyskinesia which exhibited the phenotype of anxiety disorder
por: Kunii, Yasuto, et al.
Publicado: (2017)

Co-expression of S100A14 and S100A16 correlates with a poor prognosis in human breast cancer and promotes cancer cell invasion
por: Tanaka, Mizuko, et al.
Publicado: (2015)

The influence of tissue pH and RNA integrity number on gene expression of human postmortem brain
por: Miyahara, Kazusa, et al.
Publicado: (2023)

PM516. Association of DNA Methylation of Taq1A in the DRD2 with Response to Aripiprazole in acute schizophrenia
por: Miura, Itaru, et al.
Publicado: (2016)

Editorial: Molecular pathology in psychiatric diseases: frontiers of postmortem brain research
por: Kunii, Yasuto, et al.
Publicado: (2023)

Young patient with treatment-resistant schizophrenia drastically improved by combination of clozapine and maintenance electroconvulsive therapy: a case report
por: Ito, Masashi, et al.
Publicado: (2019)

Assessment of copy number variations in the brain genome of schizophrenia patients
por: Sakai, Miwako, et al.
Publicado: (2015)

Investigation of betaine as a novel psychotherapeutic for schizophrenia
por: Ohnishi, Tetsuo, et al.
Publicado: (2019)

The Tight-Junction Protein Claudin-6 Induces Epithelial Differentiation from Mouse F9 and Embryonic Stem Cells
por: Sugimoto, Kotaro, et al.
Publicado: (2013)

Thyroid-stimulating hormone elevation misdiagnosed as subclinical hypothyroidism following non-convulsive status epilepticus: a case report
por: Wada, Akira, et al.
Publicado: (2011)

Hashimoto encephalopathy with high plasma monoamine metabolite levels: a case report
por: Horikoshi, Sho, et al.
Publicado: (2017)

Possible Involvement of Tight Junctions, Extracellular Matrix and Nuclear Receptors in Epithelial Differentiation
por: Ichikawa-Tomikawa, Naoki, et al.
Publicado: (2011)

The efficacy of antipsychotics for prolonged delirium with renal dysfunction
por: Asano, Satoko, et al.
Publicado: (2017)

Differential diagnosis of memory impairment in areas affected by a natural disaster: a case report
por: Miyagawa, Akemi, et al.
Publicado: (2021)

Lessons learned from psychosocial support and mental health surveys during the 10 years since the Great East Japan Earthquake: Establishing evidence‐based disaster psychiatry
por: Kunii, Yasuto, et al.
Publicado: (2022)

Lipid‐correlated alterations in the transcriptome are enriched in several specific pathways in the postmortem prefrontal cortex of Japanese patients with schizophrenia
por: Arihisa, Wataru, et al.
Publicado: (2023)

PKC and PKA Phosphorylation Affect the Subcellular Localization of Claudin-1 in Melanoma Cells
por: French, Amanda D., et al.
Publicado: (2009)

COMT Val 108/158 Met polymorphism and treatment response to aripiprazole in patients with acute schizophrenia
por: Kaneko, Haruka, et al.
Publicado: (2018)

Prognostic Significance of Aberrant Claudin-6 Expression in Endometrial Cancer
por: Kojima, Manabu, et al.
Publicado: (2020)

Effects of the Great East Japan Earthquake and the Fukushima Daiichi Nuclear Power Plant accident on behavioural and psychological symptoms of dementia among patients
por: Miyagawa, Akemi, et al.
Publicado: (2021)

Long-term observation of mortality among inpatients evacuated from psychiatric hospitals in Fukushima prefecture following the Fukushima nuclear disaster
por: Terui, Toshihiro, et al.
Publicado: (2021)

Severe Psychological Distress of Evacuees in Evacuation Zone Caused by the Fukushima Daiichi Nuclear Power Plant Accident: The Fukushima Health Management Survey
por: Kunii, Yasuto, et al.
Publicado: (2016)

Decreased 16:0/20:4-phosphatidylinositol level in the post-mortem prefrontal cortex of elderly patients with schizophrenia
por: Matsumoto, Junya, et al.
Publicado: (2017)

ACUTE SCHIZOPHRENIC EPISODES—ARE THEY SCHIZOPHRENIC?
por: Singh, Gurmeet, et al.
Publicado: (1981)

EMID1, a multifunctional molecule identified in a murine model for the invasion independent metastasis pathway
por: Kawata, Takuya, et al.
Publicado: (2021)

The claudin–transcription factor signaling pathway
por: Sugimoto, Kotaro, et al.
Publicado: (2021)

Addendum: Manabu, K., et al. Prognostic Significance of Aberrant Claudin-6 Expression in Endometrial Cancer. Cancers 2020, 12, 2748
por: Kojima, Manabu, et al.
Publicado: (2021)

High-sucrose diets contribute to brain angiopathy with impaired glucose uptake and psychosis-related higher brain dysfunctions in mice
por: Hirai, Shinobu, et al.
Publicado: (2021)

Soluble JAM-C Ectodomain Serves as the Niche for Adipose-Derived Stromal/Stem Cells
por: Yamazaki, Morio, et al.
Publicado: (2021)

MicroRNA-5572 Is a Novel MicroRNA-Regulating SLC30A3 in Sporadic Amyotrophic Lateral Sclerosis
por: Kurita, Hisaka, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3brop4c7el0u5g82kpse03ecji