Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer

OBJECTIVES: Anti-epidermal growth factor receptor (EGFR) therapy has been found to be more effective against left-sided colorectal cancer (LCRC) than right-sided colorectal cancer (RCRC). We hypothesized that RCRC is more likely to harbor genetic alterations associated with resistance to anti-EGFR t...

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Detalles Bibliográficos
Autores principales: Shimada, Yoshifumi, Kameyama, Hitoshi, Nagahashi, Masayuki, Ichikawa, Hiroshi, Muneoka, Yusuke, Yagi, Ryoma, Tajima, Yosuke, Okamura, Takuma, Nakano, Masato, Sakata, Jun, Kobayashi, Takashi, Nogami, Hitoshi, Maruyama, Satoshi, Takii, Yasumasa, Hayashida, Tetsu, Takaishi, Hiromasa, Kitagawa, Yuko, Oki, Eiji, Konishi, Tsuyoshi, Ishida, Fumio, Kudo, Shin-ei, Ring, Jennifer E., Protopopov, Alexei, Lyle, Stephen, Ling, Yiwei, Okuda, Shujiro, Ishikawa, Takashi, Akazawa, Kohei, Takabe, Kazuaki, Wakai, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706819/
https://www.ncbi.nlm.nih.gov/pubmed/29212173
http://dx.doi.org/10.18632/oncotarget.20510

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