Cargando…

Melatonin attenuates hypoxia-induced epithelial-mesenchymal transition and cell aggressive via Smad7/ CCL20 in glioma

Tumor recurrence in gliomas is partly attributed to increased epithelial–mesenchymal transition (EMT) and enhanced tumor cell dissemination in the adjacent brain parenchyma. Thus, exploring effective strategies for against EMT-like changes in glioma invasion and recurrence will be important for glio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Xueran, Wang, Zhen, Ma, Huihui, Zhang, Shangrong, Yang, Haoran, Wang, Hongzhi, Fang, Zhiyou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706820/ https://www.ncbi.nlm.nih.gov/pubmed/29212174 http://dx.doi.org/10.18632/oncotarget.20525

Ejemplares similares

Supervillin promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma in hypoxia via activation of the RhoA/ROCK-ERK/p38 pathway
por: Chen, Xueran, et al.
Publicado: (2018)

DHHC protein family targets different subsets of glioma stem cells in specific niches
por: Chen, Xueran, et al.
Publicado: (2019)

Specific Glioma Prognostic Subtype Distinctions Based on DNA Methylation Patterns
por: Chen, Xueran, et al.
Publicado: (2019)

Heterogeneity of subsets in glioblastoma mediated by Smad3 palmitoylation
por: Fan, Xiaoqing, et al.
Publicado: (2021)

Correction: Heterogeneity of subsets in glioblastoma mediated by Smad3 palmitoylation
por: Fan, Xiaoqing, et al.
Publicado: (2021)

A central role for MeCP2 in the epigenetic repression of miR-200c during epithelial-to-mesenchymal transition of glioma
por: Bian, Erbao, et al.
Publicado: (2019)

Systematic transcriptome profiling of pyroptosis related signature for predicting prognosis and immune landscape in lower grade glioma
por: Yu, Huihan, et al.
Publicado: (2022)

Systematic Profiling of Alternative mRNA Splicing Signature for Predicting Glioblastoma Prognosis
por: Chen, Xueran, et al.
Publicado: (2019)

Protein Palmitoylation Regulates Cell Survival by Modulating XBP1 Activity in Glioblastoma Multiforme
por: Chen, Xueran, et al.
Publicado: (2020)

Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate
por: Hu, Lei, et al.
Publicado: (2020)

Overexpression of SMC4 activates TGFβ/Smad signaling and promotes aggressive phenotype in glioma cells
por: Jiang, L, et al.
Publicado: (2017)

CCL20 mediates RANK/RANKL-induced epithelial-mesenchymal transition in endometrial cancer cells
por: Liu, Yao, et al.
Publicado: (2016)

Melatonin Synergizes With Mesenchymal Stromal Cells Attenuates Chronic Allograft Vasculopathy
por: Qin, Ya-fei, et al.
Publicado: (2021)

The polysaccharides from Grifola frondosa attenuate CCl(4)-induced hepatic fibrosis in rats via the TGF-β/Smad signaling pathway
por: Li, Chao, et al.
Publicado: (2019)

CCL20 promotes lung adenocarcinoma progression by driving epithelial-mesenchymal transition
por: Fan, Tao, et al.
Publicado: (2022)

Correction: Overexpression of SMC4 activates TGFβ/Smad signaling and promotes aggressive phenotype in glioma cells
por: Jiang, L., et al.
Publicado: (2022)

Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression
por: Chen, Xueran, et al.
Publicado: (2020)

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation
por: Fan, Xiaoqing, et al.
Publicado: (2021)

Corrigendum: Melatonin Synergizes With Mesenchymal Stromal Cells Attenuates Chronic Allograft Vasculopathy
por: Qin, Ya-fei, et al.
Publicado: (2021)

Melatonin Attenuates Dysregulation of the Circadian Clock Pathway in Mice With CCl(4)-Induced Fibrosis and Human Hepatic Stellate Cells
por: González-Fernández, Bárbara, et al.
Publicado: (2018)

Glucocorticoids promote CCL20 expression in keratinocytes
por: Wang, L., et al.
Publicado: (2021)

CITED2 attenuates macrophage recruitment concordant with the downregulation of CCL20 in breast cancer cells
por: Jayaraman, Swaathi, et al.
Publicado: (2018)

Hypoxia induces calpain activity and degrades SMAD2 to attenuate TGFβ signaling in macrophages
por: Cui, Wei, et al.
Publicado: (2015)

Retraction: Melatonin attenuates dysregulation of the circadian clock pathway in mice with CCl4-induced fibrosis and human hepatic stellate cells
por: Frontiers Editorial Office
Publicado: (2023)

MicroRNA-92a Inhibition Attenuates Hypoxia/Reoxygenation-Induced Myocardiocyte Apoptosis by Targeting Smad7
por: Zhang, Busheng, et al.
Publicado: (2014)

Schisandrin B attenuates CCl(4)-induced liver fibrosis in rats by regulation of Nrf2-ARE and TGF-β/Smad signaling pathways
por: Chen, Qingshan, et al.
Publicado: (2017)

Melatonin Attenuates Intermittent Hypoxia-Induced Lipid Peroxidation and Local Inflammation in Rat Adrenal Medulla
por: Liu, Yu, et al.
Publicado: (2014)

Super-enhancer-driven lncRNA LIMD1-AS1 activated by CDK7 promotes glioma progression
por: Chen, Zhigang, et al.
Publicado: (2023)

FDPS promotes glioma growth and macrophage recruitment by regulating CCL20 via Wnt/β‐catenin signalling pathway
por: Chen, Zhuo, et al.
Publicado: (2020)

Ccl5 establishes an autocrine high-grade glioma growth regulatory circuit critical for mesenchymal glioblastoma survival
por: Pan, Yuan, et al.
Publicado: (2017)

Cigarette smoke-induced chronic obstructive pulmonary disease is attenuated by CCL20-blocker: a rat model
por: Sun, Desheng, et al.
Publicado: (2016)

Local hyperthermia decreases the expression of CCL-20 in condyloma acuminatum
por: Wang, Xiaoqin, et al.
Publicado: (2010)

DCE-MRI of Tumor Hypoxia and Hypoxia-Associated Aggressiveness
por: Gaustad, Jon-Vidar, et al.
Publicado: (2020)

D-Carvone Attenuates CCl(4)-Induced Liver Fibrosis in Rats by Inhibiting Oxidative Stress and TGF-ß 1/SMAD3 Signaling Pathway
por: Ogaly, Hanan A., et al.
Publicado: (2022)

Repression of Smad3 by silencing Robo1 attenuates epithelial-mesenchymal transition in tracheobronchial stenosis
por: He, Chunyan, et al.
Publicado: (2023)

Melatonin influences the biological characteristics of keloid fibroblasts through the Erk and Smad signalling pathways
por: Huang, Shaobin, et al.
Publicado: (2023)

Hypoxia directed migration of human naïve monocytes is associated with an attenuation of cytokine release: indications for a key role of CCL26
por: Hummitzsch, Lars, et al.
Publicado: (2020)

Suppression of ADAM8 attenuates angiotensin II-induced cardiac fibrosis and endothelial-mesenchymal transition via inhibiting TGF-β1/Smad2/Smad3 pathways
por: Yao, Lixia, et al.
Publicado: (2021)

The CCL20-CCR6 Axis in Cancer Progression
por: Kadomoto, Suguru, et al.
Publicado: (2020)

TGF-β2 initiates autophagy via Smad and non-Smad pathway to promote glioma cells’ invasion
por: Zhang, Chao, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ndb42sckj5b0g1ul3id4ngr7ln