Oncogenic p95HER2/611CTF primes human breast epithelial cells for metabolic stress-induced down-regulation of FLIP and activation of TRAIL-R/Caspase-8-dependent apoptosis

Oncogenic transformation triggers reprogramming of cell metabolism, as part of the tumorigenic process. However, metabolic reprogramming may also increase the sensitivity of transformed cells to microenvironmental stress, at the early stages of tumor development. Herein, we show that transformation...

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Detalles Bibliográficos
Autores principales: Martín-Pérez, Rosa, Yerbes, Rosario, Mora-Molina, Rocío, Cano-González, Ana, Arribas, Joaquín, Mazzone, Massimiliano, López-Rivas, Abelardo, Palacios, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706828/
https://www.ncbi.nlm.nih.gov/pubmed/29212182
http://dx.doi.org/10.18632/oncotarget.21458

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