Klf4 reduces stemness phenotype, triggers mesenchymal-epithelial transition (MET)-like molecular changes, and prevents tumor progression in nasopharygeal carcinoma

The reprogramming factor Krüppel-like factor 4 (Klf4), one of the Yamanaka's reprogramming factors, plays an essential role in reprogramming somatic cells into induced pluripotent stem cells (iPSCs). Klf4 is dysregulated and displays divergent functions in multiple malignancies, but the biologi...

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Detalles Bibliográficos
Autores principales: Li, Xiqing, Zhao, Zhunlan, Zhang, Xiaoling, Yang, Sheng, Lin, Xia, Yang, Xinglong, Lin, Xiaolin, Shi, Junwen, Wang, Shengchun, Zhao, Wentao, Li, Jing, Gao, Fei, Liu, Mingyue, Ma, Ning, Luo, Weiren, Yao, Kaitai, Sun, Yan, Xiao, Shengjun, Xiao, Dong, Jia, Junshuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706845/
https://www.ncbi.nlm.nih.gov/pubmed/29212199
http://dx.doi.org/10.18632/oncotarget.21370

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