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ADAMTS1-mediated targeting of TSP-1 by PPARδ suppresses migration and invasion of breast cancer cells

Migration and invasion of cancer cells into surrounding tissue is a key stage of cancer metastasis. Here, we show that peroxisome proliferator-activated receptor (PPAR) δ regulates migration and invasion of human breast cancer cells via thrombospondin-1 (TSP-1) and its degrading protease, a disinteg...

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Detalles Bibliográficos
Autores principales: Ham, Sun Ah, Yoo, Taesik, Lee, Won Jin, Hwang, Jung Seok, Hur, Jinwoo, Paek, Kyung Shin, Lim, Dae-Seog, Han, Sung Gu, Lee, Chi-Ho, Seo, Han Geuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706858/
https://www.ncbi.nlm.nih.gov/pubmed/29212212
http://dx.doi.org/10.18632/oncotarget.21584