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Shift in energy metabolism caused by glucocorticoids enhances the effect of cytotoxic anti-cancer drugs against acute lymphoblastic leukemia cells

Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. Treatments include glucocorticoids (GCs) such as dexamethasone (Dex) and prednisolone, which may be of value when used alongside cytotoxic anti-cancer drugs. To predict therapeutic efficacy of GCs, their activity against ALL...

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Detalles Bibliográficos
Autores principales:	Aoki, Shigeki, Morita, Michie, Hirao, Takuya, Yamaguchi, Masashi, Shiratori, Reika, Kikuya, Megumi, Chibana, Hiroji, Ito, Kousei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706873/ https://www.ncbi.nlm.nih.gov/pubmed/29212227 http://dx.doi.org/10.18632/oncotarget.21689

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