EWS-FLI1 and RNA helicase A interaction inhibitor YK-4-279 inhibits growth of neuroblastoma

Treatment failure in high risk neuroblastoma (NB) is largely due to the development of chemotherapy resistance. We analyzed the gene expression changes associated with exposure to chemotherapy in six high risk NB tumors with the aid of the Connectivity Map bioinformatics platform. Ten therapeutic ag...

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Detalles Bibliográficos
Autores principales: Sun, Wenjing, Rojas, Yesenia, Wang, Hao, Yu, Yang, Wang, Yongfeng, Chen, Zhenghu, Rajapakshe, Kimal, Xu, Xin, Huang, Wei, Agarwal, Saurabh, Patel, Roma H., Woodfield, Sarah, Zhao, Yanling, Jin, Jingling, Zhang, Hong, Major, Angela, Hicks, M. John, Shohet, Jason M., Vasudevan, Sanjeev A., Coarfa, Cristian, Yang, Jianhua, Nuchtern, Jed G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706912/
https://www.ncbi.nlm.nih.gov/pubmed/29212266
http://dx.doi.org/10.18632/oncotarget.21933

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