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Linking H1 with chromatin and growth control

The retinoblastoma protein (pRb) is considered to be one of the key regulators of cell proliferation. Here we describe our recent findings that linker histone H1.2 is an interaction partner for pRb and impacts upon the genome-wide chromatin binding properties of pRb. Consequently, H1.2 influences tr...

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Detalles Bibliográficos
Autores principales: Munro, Shonagh, La Thangue, Nicholas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706956/
https://www.ncbi.nlm.nih.gov/pubmed/29209648
http://dx.doi.org/10.1080/23723556.2017.1360977

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