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EV20-Sap, a novel anti-HER-3 antibody-drug conjugate, displays promising antitumor activity in melanoma

Melanoma is the most biologically aggressive skin cancer of well established constitutive and induced resistance to pharmacological treatment. Despite the recent progresses in immunotherapies, many advanced metastatic melanoma patients still face a significant mortality risk. The aggressive nature o...

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Detalles Bibliográficos
Autores principales: Capone, Emily, Giansanti, Francesco, Ponziani, Sara, Lamolinara, Alessia, Iezzi, Manuela, Cimini, Annamaria, Angelucci, Francesco, Sorda, Rossana La, Laurenzi, Vincenzo De, Natali, Pier Giorgio, Ippoliti, Rodolfo, Iacobelli, Stefano, Sala, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707031/
https://www.ncbi.nlm.nih.gov/pubmed/29221137
http://dx.doi.org/10.18632/oncotarget.20728