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High PTPN13 expression in high grade serous ovarian carcinoma is associated with a better patient outcome

BACKGROUND: Chromosome 4q loss of heterozygosity (LOH) is frequently observed in high-grade serous ovarian carcinoma (HGSOC). However, this LOH has not been clearly associated with the inactivation of any tumor suppressor gene(s). As the tumor suppressor gene PTPN13 is located on chromosome 4q21, we...

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Detalles Bibliográficos
Autores principales: D’Hondt, Véronique, Lacroix-Triki, Magalie, Jarlier, Marta, Boissiere-Michot, Florence, Puech, Carole, Coopman, Peter, Katsaros, Dionyssios, Freiss, Gilles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707051/
https://www.ncbi.nlm.nih.gov/pubmed/29221157
http://dx.doi.org/10.18632/oncotarget.21175