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Selection and characterization of a human ovarian cancer cell line resistant to auranofin

The anti-arthritic drug auranofin exerts also potent antitumour activity in in vitro and in vivo models, whose mechanisms are not yet well defined. From an auranofin-sensitive human ovarian cancer cell line A2780, a highly resistant (>20-fold) subline (A2780/AF-R) was developed and characterized....

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Detalles Bibliográficos
Autores principales:	Landini, Ida, Lapucci, Andrea, Pratesi, Alessandro, Massai, Lara, Napoli, Cristina, Perrone, Gabriele, Pinzani, Pamela, Messori, Luigi, Mini, Enrico, Nobili, Stefania
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707081/ https://www.ncbi.nlm.nih.gov/pubmed/29221187 http://dx.doi.org/10.18632/oncotarget.21708

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