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EZH2 alteration driven by microRNA-524-5p and microRNA-324-5p promotes cell proliferation and temozolomide resistance in glioma
Recent data have been shown that EZH2 is a critical oncogene via the repression of tumor suppressor genes in human cancers. In our study, we performed a genome-wide miRNA screen with a bioinformatics analysis to identify EZH2 specific miRNAs. Of these miRNAs, miR-524-5p and miR-324-5p were decreased...
Autores principales: | Zhi, Tongle, Yu, Tianfu, Pan, Minhong, Nie, Er, Wu, Weining, Wang, Xiefeng, Liu, Ning, You, Yongping, Wang, Yingyi, Zhang, Junxia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707096/ https://www.ncbi.nlm.nih.gov/pubmed/29221202 http://dx.doi.org/10.18632/oncotarget.21996 |
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