Direct HPV E6/Myc interactions induce histone modifications, Pol II phosphorylation, and hTERT promoter activation

Human Papillomavirus Viruses (HPVs) are associated with the majority of human cervical and anal cancers and 10-30% of head and neck squamous carcinomas. E6 oncoprotein from high risk HPVs interacts with the p53 tumor suppressor protein to facilitate its degradation and increases telomerase activity...

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Detalles Bibliográficos
Autores principales: Zhang, Yiyu, Dakic, Aleksandra, Chen, Renxiang, Dai, Yuhai, Schlegel, Richard, Liu, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707103/
https://www.ncbi.nlm.nih.gov/pubmed/29221209
http://dx.doi.org/10.18632/oncotarget.22036

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