Non ictal onset zone: A window to ictal dynamics()

The focal and network concepts of epilepsy present different aspects of electroclinical phenomenon of seizures. Here, we present a 23-year-old man undergoing surgical evaluation with left fronto-temporal electrocorticography (ECoG) and microelectrode-array (MEA) in the middle temporal gyrus (MTG). W...

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Detalles Bibliográficos
Autores principales: Afra, Pegah, Hanrahan, Sara J., Kellis, Spencer Sterling, House, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707213/
https://www.ncbi.nlm.nih.gov/pubmed/29204348
http://dx.doi.org/10.1016/j.ebcr.2017.10.003
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author Afra, Pegah
Hanrahan, Sara J.
Kellis, Spencer Sterling
House, Paul
author_facet Afra, Pegah
Hanrahan, Sara J.
Kellis, Spencer Sterling
House, Paul
author_sort Afra, Pegah
collection PubMed
description The focal and network concepts of epilepsy present different aspects of electroclinical phenomenon of seizures. Here, we present a 23-year-old man undergoing surgical evaluation with left fronto-temporal electrocorticography (ECoG) and microelectrode-array (MEA) in the middle temporal gyrus (MTG). We compare action-potential (AP) and local field potentials (LFP) recorded from MEA with ECoG. Seizure onset in the mesial-temporal lobe was characterized by changes in the pattern of AP-firing without clear changes in LFP or ECoG in MTG. This suggests simultaneous analysis of neuronal activity in differing spatial scales and frequency ranges provide complementary insights into how focal and network neurophysiological activity contribute to ictal activity.
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spelling pubmed-57072132017-12-04 Non ictal onset zone: A window to ictal dynamics() Afra, Pegah Hanrahan, Sara J. Kellis, Spencer Sterling House, Paul Epilepsy Behav Case Rep Article The focal and network concepts of epilepsy present different aspects of electroclinical phenomenon of seizures. Here, we present a 23-year-old man undergoing surgical evaluation with left fronto-temporal electrocorticography (ECoG) and microelectrode-array (MEA) in the middle temporal gyrus (MTG). We compare action-potential (AP) and local field potentials (LFP) recorded from MEA with ECoG. Seizure onset in the mesial-temporal lobe was characterized by changes in the pattern of AP-firing without clear changes in LFP or ECoG in MTG. This suggests simultaneous analysis of neuronal activity in differing spatial scales and frequency ranges provide complementary insights into how focal and network neurophysiological activity contribute to ictal activity. Elsevier 2017-10-21 /pmc/articles/PMC5707213/ /pubmed/29204348 http://dx.doi.org/10.1016/j.ebcr.2017.10.003 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Afra, Pegah
Hanrahan, Sara J.
Kellis, Spencer Sterling
House, Paul
Non ictal onset zone: A window to ictal dynamics()
title Non ictal onset zone: A window to ictal dynamics()
title_full Non ictal onset zone: A window to ictal dynamics()
title_fullStr Non ictal onset zone: A window to ictal dynamics()
title_full_unstemmed Non ictal onset zone: A window to ictal dynamics()
title_short Non ictal onset zone: A window to ictal dynamics()
title_sort non ictal onset zone: a window to ictal dynamics()
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707213/
https://www.ncbi.nlm.nih.gov/pubmed/29204348
http://dx.doi.org/10.1016/j.ebcr.2017.10.003
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AT hanrahansaraj nonictalonsetzoneawindowtoictaldynamics
AT kellisspencersterling nonictalonsetzoneawindowtoictaldynamics
AT housepaul nonictalonsetzoneawindowtoictaldynamics

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