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Low-Energy Collisions of Protonated Enantiopure Amino Acids with Chiral Target Gases

Here we report on the gas-phase interactions between protonated enantiopure amino acids (l- and d-enantiomers of Met, Phe, and Trp) and chiral target gases [(R)- and (S)-2-butanol, and (S)-1-phenylethanol] in 0.1–10.0 eV low-energy collisions. Two major processes are seen to occur over this collisio...

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Autores principales: Kulyk, K., Rebrov, O., Ryding, M., Thomas, R. D., Uggerud, E., Larsson, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707228/
https://www.ncbi.nlm.nih.gov/pubmed/28936701
http://dx.doi.org/10.1007/s13361-017-1796-7
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author Kulyk, K.
Rebrov, O.
Ryding, M.
Thomas, R. D.
Uggerud, E.
Larsson, M.
author_facet Kulyk, K.
Rebrov, O.
Ryding, M.
Thomas, R. D.
Uggerud, E.
Larsson, M.
author_sort Kulyk, K.
collection PubMed
description Here we report on the gas-phase interactions between protonated enantiopure amino acids (l- and d-enantiomers of Met, Phe, and Trp) and chiral target gases [(R)- and (S)-2-butanol, and (S)-1-phenylethanol] in 0.1–10.0 eV low-energy collisions. Two major processes are seen to occur over this collision energy regime, collision-induced dissociation and ion-molecule complex formation. Both processes were found to be independent of the stereo-chemical composition of the interacting ions and targets. These data shed light on the currently debated mechanisms of gas-phase chiral selectivity by demonstrating the inapplicability of the three-point model to these interactions, at least under single collision conditions. [Figure: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s13361-017-1796-7) contains supplementary material, which is available to authorized users.
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spelling pubmed-57072282017-12-04 Low-Energy Collisions of Protonated Enantiopure Amino Acids with Chiral Target Gases Kulyk, K. Rebrov, O. Ryding, M. Thomas, R. D. Uggerud, E. Larsson, M. J Am Soc Mass Spectrom Research Article Here we report on the gas-phase interactions between protonated enantiopure amino acids (l- and d-enantiomers of Met, Phe, and Trp) and chiral target gases [(R)- and (S)-2-butanol, and (S)-1-phenylethanol] in 0.1–10.0 eV low-energy collisions. Two major processes are seen to occur over this collision energy regime, collision-induced dissociation and ion-molecule complex formation. Both processes were found to be independent of the stereo-chemical composition of the interacting ions and targets. These data shed light on the currently debated mechanisms of gas-phase chiral selectivity by demonstrating the inapplicability of the three-point model to these interactions, at least under single collision conditions. [Figure: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s13361-017-1796-7) contains supplementary material, which is available to authorized users. Springer US 2017-09-21 2017 /pmc/articles/PMC5707228/ /pubmed/28936701 http://dx.doi.org/10.1007/s13361-017-1796-7 Text en © The Author(s) 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Research Article
Kulyk, K.
Rebrov, O.
Ryding, M.
Thomas, R. D.
Uggerud, E.
Larsson, M.
Low-Energy Collisions of Protonated Enantiopure Amino Acids with Chiral Target Gases
title Low-Energy Collisions of Protonated Enantiopure Amino Acids with Chiral Target Gases
title_full Low-Energy Collisions of Protonated Enantiopure Amino Acids with Chiral Target Gases
title_fullStr Low-Energy Collisions of Protonated Enantiopure Amino Acids with Chiral Target Gases
title_full_unstemmed Low-Energy Collisions of Protonated Enantiopure Amino Acids with Chiral Target Gases
title_short Low-Energy Collisions of Protonated Enantiopure Amino Acids with Chiral Target Gases
title_sort low-energy collisions of protonated enantiopure amino acids with chiral target gases
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707228/
https://www.ncbi.nlm.nih.gov/pubmed/28936701
http://dx.doi.org/10.1007/s13361-017-1796-7
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