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Digoxin enhances radiation response in radioresistant A549 cells by reducing protein phosphatase 2A

Protein phosphatase 2A (PP2A) is a ubiquitous multifunctional enzyme usually known as a tumor suppressor. Recent studies have reported that although inhibition of PP2A leads to acceleration of cell growth, it also induces damaged cells to pass through the cell cycle and renders them sensitive to rad...

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Detalles Bibliográficos
Autores principales: Lee, Ji Young, Kim, Mi-Sook, Lee, Mi So, Ju, Jae Eun, Chung, Namhyun, Jeong, Youn Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707360/
https://www.ncbi.nlm.nih.gov/pubmed/29070518
http://dx.doi.org/10.1042/BSR20171257