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Reprogramming to pluripotency does not require transition through a primitive streak-like state

Pluripotency can be induced in vitro from adult somatic mammalian cells by enforced expression of defined transcription factors regulating and initiating the pluripotency network. Despite the substantial advances over the last decade to improve the efficiency of direct reprogramming, exact mechanism...

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Detalles Bibliográficos
Autores principales:	Raab, Stefanie, Klingenstein, Moritz, Möller, Anna, Illing, Anett, Tosic, Jelena, Breunig, Markus, Kuales, Georg, Linta, Leonhard, Seufferlein, Thomas, Arnold, Sebastian J., Kleger, Alexander, Liebau, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707390/ https://www.ncbi.nlm.nih.gov/pubmed/29185460 http://dx.doi.org/10.1038/s41598-017-15187-x

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