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Hyperpolarization of amino acid derivatives in water for biological applications

We report on the successful synthesis and hyperpolarization of N-unprotected α-amino acid ethyl propionate esters and extensively, on an alanine derivative hyperpolarized by PHIP (4.4 ± 1.0% (13)C-polarization), meeting required levels for in vivo detection. Using water as solvent increases biocompa...

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Detalles Bibliográficos
Autores principales:	Glöggler, S., Wagner, S., Bouchard, L.-S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2015
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707458/ https://www.ncbi.nlm.nih.gov/pubmed/29218193 http://dx.doi.org/10.1039/c5sc00503e

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