Highly enantioselective sulfa-Michael addition reactions using N-heterocyclic carbene as a non-covalent organocatalyst

We report the first asymmetric sulfa-Michael addition (SMA) reactions using a chiral N-heterocyclic carbene (NHC) as a non-covalent organocatalyst. We demonstrate that a triazolium salt derived NHC functions as an excellent Brønsted base to promote enantioselective carbon–sulfur bond formation. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Jiean, Meng, Sixuan, Wang, Leming, Tang, Hongmei, Huang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707481/
https://www.ncbi.nlm.nih.gov/pubmed/29218184
http://dx.doi.org/10.1039/c5sc00878f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707481/
https://www.ncbi.nlm.nih.gov/pubmed/29218184
http://dx.doi.org/10.1039/c5sc00878f

Ejemplares similares