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Highly enantioselective sulfa-Michael addition reactions using N-heterocyclic carbene as a non-covalent organocatalyst

We report the first asymmetric sulfa-Michael addition (SMA) reactions using a chiral N-heterocyclic carbene (NHC) as a non-covalent organocatalyst. We demonstrate that a triazolium salt derived NHC functions as an excellent Brønsted base to promote enantioselective carbon–sulfur bond formation. The...

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Detalles Bibliográficos
Autores principales:	Chen, Jiean, Meng, Sixuan, Wang, Leming, Tang, Hongmei, Huang, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2015
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707481/ https://www.ncbi.nlm.nih.gov/pubmed/29218184 http://dx.doi.org/10.1039/c5sc00878f

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