Palladium-catalyzed reductive coupling of phenols with anilines and amines: efficient conversion of phenolic lignin model monomers and analogues to cyclohexylamines

Phenols, being readily available from naturally abundant lignins, are important future feedstocks for the renewable production of fuels, chemicals, and energy. Herein, a highly efficient Pd-catalyzed direct coupling of phenolic lignin model monomers and analogues with anilines to give cyclohexylamin...

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Autores principales: Chen, Zhengwang, Zeng, Huiying, Gong, Hang, Wang, Haining, Li, Chao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707487/
https://www.ncbi.nlm.nih.gov/pubmed/29218182
http://dx.doi.org/10.1039/c5sc00941c
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author Chen, Zhengwang
Zeng, Huiying
Gong, Hang
Wang, Haining
Li, Chao-Jun
author_facet Chen, Zhengwang
Zeng, Huiying
Gong, Hang
Wang, Haining
Li, Chao-Jun
author_sort Chen, Zhengwang
collection PubMed
description Phenols, being readily available from naturally abundant lignins, are important future feedstocks for the renewable production of fuels, chemicals, and energy. Herein, a highly efficient Pd-catalyzed direct coupling of phenolic lignin model monomers and analogues with anilines to give cyclohexylamines using cheap and safe sodium formate as hydrogen donor is described. A variety of secondary and tertiary substituted cyclohexylamines can be synthesized under convenient conditions in moderate to excellent yields.
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spelling pubmed-57074872017-12-07 Palladium-catalyzed reductive coupling of phenols with anilines and amines: efficient conversion of phenolic lignin model monomers and analogues to cyclohexylamines Chen, Zhengwang Zeng, Huiying Gong, Hang Wang, Haining Li, Chao-Jun Chem Sci Chemistry Phenols, being readily available from naturally abundant lignins, are important future feedstocks for the renewable production of fuels, chemicals, and energy. Herein, a highly efficient Pd-catalyzed direct coupling of phenolic lignin model monomers and analogues with anilines to give cyclohexylamines using cheap and safe sodium formate as hydrogen donor is described. A variety of secondary and tertiary substituted cyclohexylamines can be synthesized under convenient conditions in moderate to excellent yields. Royal Society of Chemistry 2015-07-01 2015-04-30 /pmc/articles/PMC5707487/ /pubmed/29218182 http://dx.doi.org/10.1039/c5sc00941c Text en This journal is © The Royal Society of Chemistry 2015 http://creativecommons.org/licenses/by-nc/3.0/ This article is freely available. This article is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported Licence (CC BY-NC 3.0)
spellingShingle Chemistry
Chen, Zhengwang
Zeng, Huiying
Gong, Hang
Wang, Haining
Li, Chao-Jun
Palladium-catalyzed reductive coupling of phenols with anilines and amines: efficient conversion of phenolic lignin model monomers and analogues to cyclohexylamines
title Palladium-catalyzed reductive coupling of phenols with anilines and amines: efficient conversion of phenolic lignin model monomers and analogues to cyclohexylamines
title_full Palladium-catalyzed reductive coupling of phenols with anilines and amines: efficient conversion of phenolic lignin model monomers and analogues to cyclohexylamines
title_fullStr Palladium-catalyzed reductive coupling of phenols with anilines and amines: efficient conversion of phenolic lignin model monomers and analogues to cyclohexylamines
title_full_unstemmed Palladium-catalyzed reductive coupling of phenols with anilines and amines: efficient conversion of phenolic lignin model monomers and analogues to cyclohexylamines
title_short Palladium-catalyzed reductive coupling of phenols with anilines and amines: efficient conversion of phenolic lignin model monomers and analogues to cyclohexylamines
title_sort palladium-catalyzed reductive coupling of phenols with anilines and amines: efficient conversion of phenolic lignin model monomers and analogues to cyclohexylamines
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707487/
https://www.ncbi.nlm.nih.gov/pubmed/29218182
http://dx.doi.org/10.1039/c5sc00941c
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