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Characterization of Nucleoside Reverse Transcriptase Inhibitor-Associated Mutations in the RNase H Region of HIV-1 Subtype C Infected Individuals

The South African national treatment programme includes nucleoside reverse transcriptase inhibitors (NRTIs) in both first and second line highly active antiretroviral therapy regimens. Mutations in the RNase H domain have been associated with resistance to NRTIs but primarily in HIV-1 subtype B stud...

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Detalles Bibliográficos
Autores principales: Ngcapu, Sinaye, Theys, Kristof, Libin, Pieter, Marconi, Vincent C., Sunpath, Henry, Ndung’u, Thumbi, Gordon, Michelle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707537/
https://www.ncbi.nlm.nih.gov/pubmed/29117130
http://dx.doi.org/10.3390/v9110330

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