Influence of VO(2) Nanoparticle Morphology on the Colorimetric Assay of H(2)O(2) and Glucose

Nanozyme-based colorimetric sensors have received considerable attention due to their unique properties. The size, shape, and surface chemistry of these nanozymes could dramatically influence their sensing behaviors. Herein, a comparative study of VO(2) nanoparticles with different morphologies (nanofibers, nanosheets, and nanorods) was conducted and applied to the sensitive colorimetric detection of H(2)O(2) and glucose. The peroxidase-like activities and mechanisms of VO(2) nanoparticles were analyzed. Among the VO(2) nanoparticles, VO(2) nanofibers exhibited the best peroxidase-like activity. Finally, a comparative quantitative detections of H(2)O(2) and glucose were done on fiber, sheet, and rod nanoparticles. Under the optimal reaction conditions, the lower limit of detection (LOD) of the VO(2) nanofibers, nanosheets, and nanorods for H(2)O(2) are found to be 0.018, 0.266, and 0.41 mM, respectively. The VO(2) nanofibers, nanosheets, and nanorods show the linear response for H(2)O(2) from 0.025–10, 0.488–62.5, and 0.488–15.625 mM, respectively. The lower limit of detection (LOD) of the VO(2) nanofibers, nanosheets, and nanorods for glucose are found to be 0.009, 0.348, and 0.437 mM, respectively. The VO(2) nanofibers, nanosheets, and nanorods show the linear response for glucose from 0.01–10, 0.625–15, and 0.625–10 mM, respectively. The proposed work will contribute to the nanozyme-based colorimetric assay.