Phosphate Promotes the Recovery of Mycobacterium tuberculosis β-Lactamase from Clavulanic Acid Inhibition

[Image: see text] The rise of multi- and even totally antibiotic resistant forms of Mycobacterium tuberculosis underlines the need for new antibiotics. The pathogen is resistant to β-lactam compounds due to its native serine β-lactamase, BlaC. This resistance can be circumvented by administration of...

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Detalles Bibliográficos
Autores principales: Elings, Wouter, Tassoni, Raffaella, van der Schoot, Steven A., Luu, Wendy, Kynast, Josef P., Dai, Lin, Blok, Anneloes J., Timmer, Monika, Florea, Bogdan I., Pannu, Navraj S., Ubbink, Marcellus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707625/
https://www.ncbi.nlm.nih.gov/pubmed/29087696
http://dx.doi.org/10.1021/acs.biochem.7b00556

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