WNT Inhibitory Activity of Malus Pumila miller cv Annurca and Malus domestica cv Limoncella Apple Extracts on Human Colon-Rectal Cells Carrying Familial Adenomatous Polyposis Mutations

Inhibitors of the Wingless-related Integration site (WNT)/β-catenin pathway have recently been under consideration as potential chemopreventive agents against Familial Adenomatous Polyposis (FAP). This autosomal-dominant syndrome is caused by germline mutations in the gene coding for the protein APC...

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Detalles Bibliográficos
Autores principales: Riccio, Gennaro, Maisto, Maria, Bottone, Sara, Badolati, Nadia, Rossi, Giovanni Battista, Tenore, Gian Carlo, Stornaiuolo, Mariano, Novellino, Ettore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707734/
https://www.ncbi.nlm.nih.gov/pubmed/29156563
http://dx.doi.org/10.3390/nu9111262

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