Cargando…

Prevalence of Pre-Diabetes across Ethnicities: A Review of Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT) for Classification of Dysglycaemia

Prediabetes can be defined by the presence of impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT), or glycated haemoglobin (Hb(A1c)) to identify individuals at increased risk of developing type 2 diabetes (T2D). The World Health Organization (WHO, 1999) and the American Diabetes A...

Descripción completa

Detalles Bibliográficos
Autores principales: Yip, Wilson C. Y., Sequeira, Ivana R., Plank, Lindsay D., Poppitt, Sally D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707745/
https://www.ncbi.nlm.nih.gov/pubmed/29165385
http://dx.doi.org/10.3390/nu9111273
_version_ 1783282501393842176
author Yip, Wilson C. Y.
Sequeira, Ivana R.
Plank, Lindsay D.
Poppitt, Sally D.
author_facet Yip, Wilson C. Y.
Sequeira, Ivana R.
Plank, Lindsay D.
Poppitt, Sally D.
author_sort Yip, Wilson C. Y.
collection PubMed
description Prediabetes can be defined by the presence of impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT), or glycated haemoglobin (Hb(A1c)) to identify individuals at increased risk of developing type 2 diabetes (T2D). The World Health Organization (WHO, 1999) and the American Diabetes Association (ADA, 2003) utilise different cut-off values for IFG (WHO: 6.1–6.9 mmol/L; ADA: 5.6–6.9 mmol/L) but the same cut-off values for IGT (7.8–11.0 mmol/L). This review investigates whether there are differences in prevalence of IFG, IGT, and combined IFG&IGT between ethnicities, in particular Asian Chinese and European Caucasians. In total, we identified 19 studies using the WHO(1999) classification, for which the average proportional prevalence for isolated (i)-IFG, i-IGT, and combined IFG&IGT were 43.9%, 41.0%, and 13.5%, respectively, for Caucasian and 29.2%, 49.4%, and 18.2%, respectively, for Asian. For the 14 studies using ADA(2003) classification, the average proportional i-IFG, i-IGT, and combined IFG&IGT prevalences were 58.0%, 20.3%, and 19.8%, respectively, for Caucasian; 48.1%, 27.7%, and 20.5%, respectively, for Asian. Whilst not statistically different, there may be clinically relevant differences in the two populations, with our observations for both classifications indicating that prevalence of i-IFG is higher in Caucasian cohorts whilst i-IGT and combined IFG&IGT are both higher in Asian cohorts.
format Online
Article
Text
id pubmed-5707745
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-57077452017-12-05 Prevalence of Pre-Diabetes across Ethnicities: A Review of Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT) for Classification of Dysglycaemia Yip, Wilson C. Y. Sequeira, Ivana R. Plank, Lindsay D. Poppitt, Sally D. Nutrients Review Prediabetes can be defined by the presence of impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT), or glycated haemoglobin (Hb(A1c)) to identify individuals at increased risk of developing type 2 diabetes (T2D). The World Health Organization (WHO, 1999) and the American Diabetes Association (ADA, 2003) utilise different cut-off values for IFG (WHO: 6.1–6.9 mmol/L; ADA: 5.6–6.9 mmol/L) but the same cut-off values for IGT (7.8–11.0 mmol/L). This review investigates whether there are differences in prevalence of IFG, IGT, and combined IFG&IGT between ethnicities, in particular Asian Chinese and European Caucasians. In total, we identified 19 studies using the WHO(1999) classification, for which the average proportional prevalence for isolated (i)-IFG, i-IGT, and combined IFG&IGT were 43.9%, 41.0%, and 13.5%, respectively, for Caucasian and 29.2%, 49.4%, and 18.2%, respectively, for Asian. For the 14 studies using ADA(2003) classification, the average proportional i-IFG, i-IGT, and combined IFG&IGT prevalences were 58.0%, 20.3%, and 19.8%, respectively, for Caucasian; 48.1%, 27.7%, and 20.5%, respectively, for Asian. Whilst not statistically different, there may be clinically relevant differences in the two populations, with our observations for both classifications indicating that prevalence of i-IFG is higher in Caucasian cohorts whilst i-IGT and combined IFG&IGT are both higher in Asian cohorts. MDPI 2017-11-22 /pmc/articles/PMC5707745/ /pubmed/29165385 http://dx.doi.org/10.3390/nu9111273 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yip, Wilson C. Y.
Sequeira, Ivana R.
Plank, Lindsay D.
Poppitt, Sally D.
Prevalence of Pre-Diabetes across Ethnicities: A Review of Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT) for Classification of Dysglycaemia
title Prevalence of Pre-Diabetes across Ethnicities: A Review of Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT) for Classification of Dysglycaemia
title_full Prevalence of Pre-Diabetes across Ethnicities: A Review of Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT) for Classification of Dysglycaemia
title_fullStr Prevalence of Pre-Diabetes across Ethnicities: A Review of Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT) for Classification of Dysglycaemia
title_full_unstemmed Prevalence of Pre-Diabetes across Ethnicities: A Review of Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT) for Classification of Dysglycaemia
title_short Prevalence of Pre-Diabetes across Ethnicities: A Review of Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT) for Classification of Dysglycaemia
title_sort prevalence of pre-diabetes across ethnicities: a review of impaired fasting glucose (ifg) and impaired glucose tolerance (igt) for classification of dysglycaemia
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707745/
https://www.ncbi.nlm.nih.gov/pubmed/29165385
http://dx.doi.org/10.3390/nu9111273
work_keys_str_mv AT yipwilsoncy prevalenceofprediabetesacrossethnicitiesareviewofimpairedfastingglucoseifgandimpairedglucosetoleranceigtforclassificationofdysglycaemia
AT sequeiraivanar prevalenceofprediabetesacrossethnicitiesareviewofimpairedfastingglucoseifgandimpairedglucosetoleranceigtforclassificationofdysglycaemia
AT planklindsayd prevalenceofprediabetesacrossethnicitiesareviewofimpairedfastingglucoseifgandimpairedglucosetoleranceigtforclassificationofdysglycaemia
AT poppittsallyd prevalenceofprediabetesacrossethnicitiesareviewofimpairedfastingglucoseifgandimpairedglucosetoleranceigtforclassificationofdysglycaemia