Cargando…

CMTM5 is downregulated and suppresses tumour growth in hepatocellular carcinoma through regulating PI3K-AKT signalling

BACKGROUND: Human chemokine like factor (CKLF)-like MAL and related proteins for vesicle trafficking transmembrane, domain-containing member 5 (CMTM5) has been shown to involved and may function as a tumour suppressor in tumorigenesis. The current study aimed to investigate the expression and functi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Gang, Dang, Chengxue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707824/ https://www.ncbi.nlm.nih.gov/pubmed/29213215 http://dx.doi.org/10.1186/s12935-017-0485-8

Ejemplares similares

CMTM3 suppresses chordoma progress through EGFR/STAT3 regulated EMT and TP53 signaling pathway
por: Yuan, Wanqiong, et al.
Publicado: (2021)

Effect of nicastrin on hepatocellular carcinoma proliferation and apoptosis through PI3K/AKT signalling pathway modulation
por: Wang, Xicheng, et al.
Publicado: (2020)

SCUBE3 downregulation modulates hepatocellular carcinoma by inhibiting CCNE1 via TGFβ/PI3K/AKT/GSK3β pathway
por: Xu, Pan, et al.
Publicado: (2022)

Suppressive effects of plumbagin on the growth of human bladder cancer cells via PI3K/AKT/mTOR signaling pathways and EMT
por: Zhang, Renjie, et al.
Publicado: (2020)

YY1 activates EMI2 and promotes the progression of cholangiocarcinoma through the PI3K/Akt signaling axis
por: Zhou, Shuai, et al.
Publicado: (2021)

Wilms’ tumour suppressor gene 1 (WT1) is involved in the carcinogenesis of Lung cancer through interaction with PI3K/Akt pathway
por: Wang, Xi, et al.
Publicado: (2013)

[6]-Paradol suppresses proliferation and metastases of pancreatic cancer by decreasing EGFR and inactivating PI3K/AKT signaling
por: Jiang, Xueyi, et al.
Publicado: (2021)

Midkine promotes glioblastoma progression via PI3K-Akt signaling
por: Hu, Beiquan, et al.
Publicado: (2021)

PGM1 suppresses colorectal cancer cell migration and invasion by regulating the PI3K/AKT pathway
por: Zheng, Zhewen, et al.
Publicado: (2022)

Targeting DNAJC19 overcomes tumor growth and lung metastasis in NSCLC by regulating PI3K/AKT signaling
por: Zhou, Ji, et al.
Publicado: (2021)

CMTM5 inhibits the development of prostate cancer via the EGFR/PI3K/AKT signaling pathway
por: Li, Linjin, et al.
Publicado: (2022)

Aloperine inhibits the progression of non-small-cell lung cancer through the PI3K/Akt signaling pathway
por: Liu, Fujuan, et al.
Publicado: (2021)

p53 sensitizes chemoresistant non-small cell lung cancer via elevation of reactive oxygen species and suppression of EGFR/PI3K/AKT signaling
por: Zhang, Yize, et al.
Publicado: (2019)

Benzimidazoisoquinoline derivatives inhibit glioblastoma cell proliferation through down-regulating Raf/MEK/ERK and PI3K/AKT pathways
por: Zhang, Ya-Jun, et al.
Publicado: (2018)

PI3-K/Akt pathway contributes to IL-6-dependent growth of 7TD1 cells
por: Zhang, JiYan, et al.
Publicado: (2003)

SH2B1 promotes NSCLC cell proliferation through PI3K/Akt/mTOR signaling cascade
por: Wang, Shaoqiang, et al.
Publicado: (2018)

miR-145 sensitizes esophageal squamous cell carcinoma to cisplatin through directly inhibiting PI3K/AKT signaling pathway
por: Zheng, Tian-Liang, et al.
Publicado: (2019)

Co-expression of CMTM6 and PD-L1: a novel prognostic indicator of gastric cancer
por: Zhang, Chao, et al.
Publicado: (2021)

Blockade of PI3K/AKT pathway enhances sensitivity of Raji cells to chemotherapy through down-regulation of HSP70
por: Fang, Xiaosheng, et al.
Publicado: (2013)

Vasodilator-stimulated phosphoprotein (VASP), a novel target of miR-4455, promotes gastric cancer cell proliferation, migration, and invasion, through activating the PI3K/AKT signaling pathway
por: Chen, Haiqun, et al.
Publicado: (2018)

Activation of EGFR-PI3K-AKT signaling is required for Mycoplasma hyorhinis-promoted gastric cancer cell migration
por: Duan, Hongying, et al.
Publicado: (2014)

SKA3 promotes cell proliferation and migration in cervical cancer by activating the PI3K/Akt signaling pathway
por: Hu, Rong, et al.
Publicado: (2018)

Knockdown of RSPH14 inhibits proliferation, migration, and invasion and promotes apoptosis of hepatocellular carcinoma via RelA
por: Yuan, Dawei, et al.
Publicado: (2022)

LPAR1 regulates the development of intratumoral heterogeneity in ovarian serous cystadenocarcinoma by activating the PI3K/AKT signaling pathway
por: Cui, Ran, et al.
Publicado: (2019)

Protopine triggers apoptosis via the intrinsic pathway and regulation of ROS/PI3K/Akt signalling pathway in liver carcinoma
por: Nie, Chunhui, et al.
Publicado: (2021)

miR-450b-5p loss mediated KIF26B activation promoted hepatocellular carcinoma progression by activating PI3K/AKT pathway
por: Li, Hua, et al.
Publicado: (2019)

Silencing of TRIM11 suppresses the tumorigenicity of chordoma cells through improving the activity of PHLPP1/AKT
por: Wang, Bin, et al.
Publicado: (2019)

miR-378d suppresses malignant phenotype of ESCC cells through AKT signaling
por: Peng, Jie, et al.
Publicado: (2021)

Downregulation of FHL1 protein in glioma inhibits tumor growth through PI3K/AKT signaling
por: Li, San-Zhong, et al.
Publicado: (2020)

Long noncoding RNA MALAT1 inhibits the apoptosis and autophagy of hepatocellular carcinoma cell by targeting the microRNA-146a/PI3K/Akt/mTOR axis
por: Peng, Ningfu, et al.
Publicado: (2020)

Celecoxib enhances anticancer effect of cisplatin and induces anoikis in osteosarcoma via PI3K/Akt pathway
por: Liu, Bing, et al.
Publicado: (2017)

Periostin promotes the proliferation and metastasis of osteosarcoma by increasing cell survival and activates the PI3K/Akt pathway
por: Xu, Chaojian, et al.
Publicado: (2022)

CMTM4 is frequently downregulated and functions as a tumour suppressor in clear cell renal cell carcinoma
por: Li, Ting, et al.
Publicado: (2015)

CircRNA PIP5K1A promotes the progression of glioma through upregulation of the TCF12/PI3K/AKT pathway by sponging miR-515-5p
por: Zheng, Kebin, et al.
Publicado: (2021)

SCD1 is required for EGFR-targeting cancer therapy of lung cancer via re-activation of EGFR/PI3K/AKT signals
por: She, Kelin, et al.
Publicado: (2019)

Cordycepin augments the chemosensitivity of osteosarcoma to cisplatin by activating AMPK and suppressing the AKT signaling pathway
por: Li, Hong-Bo, et al.
Publicado: (2021)

The differential susceptibilities of MCF-7 and MDA-MB-231 cells to the cytotoxic effects of curcumin are associated with the PI3K/Akt-SKP2-Cip/Kips pathway
por: Jia, Tao, et al.
Publicado: (2014)

miR-125a-5p post-transcriptionally suppresses GALNT7 to inhibit proliferation and invasion in cervical cancer cells via the EGFR/PI3K/AKT pathway
por: Cao, Qinxue, et al.
Publicado: (2020)

Matrine combined with cisplatin synergistically inhibited urothelial bladder cancer cells via down-regulating VEGF/PI3K/Akt signaling pathway
por: Liao, Xiao-Zhong, et al.
Publicado: (2017)

NEDD4L-induced ubiquitination mediating UBE2T degradation inhibits progression of lung adenocarcinoma via PI3K-AKT signaling
por: Chen, Yongbing, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hm4rg9igmh93mc3rqtdipgqim4